Description
Composition
Each tablet contains:
- Ondansetron USP – 8 mg
Indications (Uses)
Onitron 8 mg is indicated for the prevention and treatment of:
- Nausea and vomiting associated with chemotherapy
- Radiation-induced nausea and vomiting
- Post-operative nausea and vomiting (PONV)
- Acute nausea and vomiting due to gastroenteritis or other medical conditions (as prescribed)
Mechanism of Action
Ondansetron is a selective serotonin (5-HT3) receptor antagonist. It works by blocking serotonin receptors in the brain and gastrointestinal tract that trigger nausea and vomiting, providing fast and effective symptom relief.
Dosage and Administration
- Take as directed by your physician.
- Can be taken with or without food.
- Swallow the tablet whole with water.
- The dosage depends on the patient’s age, medical condition, and the cause of nausea or vomiting.
Common Side Effects
- Headache
- Constipation
- Dizziness
- Fatigue
- Flushing
- Mild diarrhea
Warnings and Precautions
- Use with caution in patients with liver impairment.
- May cause changes in heart rhythm (QT prolongation); caution is advised in patients with heart disease or those taking medications that affect the QT interval.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
- Seek medical attention if you experience irregular heartbeat, severe dizziness, or fainting.
Drug Interactions
Use with caution if taking:
- Other medicines that prolong the QT interval
- Apomorphine (contraindicated)
- SSRIs or SNRIs (may increase the risk of serotonin syndrome)
- Certain antiarrhythmic medications
Storage
- Store below 30°C.
- Protect from moisture and direct sunlight.
- Keep out of reach of children.
Prescription Status: Prescription-only medicine. Use only under the supervision of a qualified healthcare professional.





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