PINEFIX 100.ML SYRUP/POWDER

PineFix 100 mg/5 mL Oral Suspension

Active Ingredient: Cefixime 100 mg/5 mL
Drug Class: Third-generation cephalosporin antibiotic
Dosage Form: Powder for oral suspension
Pack Size: 60 mL after reconstitution
Flavour: Chocolate flavour

1. Indications

Cefixime is used to treat susceptible bacterial infections, including:

• Acute otitis media (middle-ear infection)
• Pharyngitis and tonsillitis
• Uncomplicated urinary tract infections (UTIs)
• Acute exacerbations of chronic bronchitis
• Uncomplicated gonorrhea, where appropriate
• Other susceptible bacterial respiratory infections as prescribed

It does not treat viral infections such as common cold or influenza.

2. Benefits

• Effective against a range of susceptible Gram-positive and Gram-negative bacteria.
• Convenient once- or twice-daily oral dosing, depending on the prescribed dose.
• Suitable for patients who require an oral cephalosporin antibiotic.
• The suspension formulation is useful for children who have difficulty swallowing tablets.

3. Contraindications

Do not use cefixime in patients with:

• Known allergy to cefixime or other cephalosporin antibiotics
• Previous severe allergic reaction to penicillins or other beta-lactam antibiotics—medical assessment is required because cross-reactivity can occur.

4. Side Effects

Common:

• Diarrhea
• Nausea
• Abdominal/stomach discomfort
• Vomiting
• Indigestion

Less common/serious:

• Skin rash or itching
• Severe allergic reaction
• Severe or persistent diarrhea, which may indicate C. difficile-associated diarrhea
• Changes in blood counts or liver function tests may rarely occur.

Seek urgent medical attention for facial/throat swelling, breathing difficulty, severe rash, or severe persistent diarrhea.

5. Warnings & Precautions

• Use only for bacterial infections confirmed or strongly suspected to be susceptible.
• Complete the prescribed course unless the doctor advises otherwise.
• Tell the doctor about any history of cephalosporin/penicillin allergy.
• Dose adjustment may be necessary in significant kidney impairment.
• Prolonged use may result in overgrowth of nonsusceptible organisms.
• If severe diarrhea occurs during or after treatment, contact a doctor rather than self-treating with anti-diarrheal medicines.

6. Usage / Dosage

Children 6 months and older: The usual cefixime dose is 8 mg/kg/day, given once daily or divided into 4 mg/kg every 12 hours, according to the doctor’s prescription.

For the 100 mg/5 mL suspension:

1 mL = 40 mg cefixime.

The exact volume depends on the child’s weight and the infection being treated.

Adults and children ≥50 kg: The usual dose is 200 mg/day, either once daily or divided into two 100 mg doses, depending on the indication.

Important: Do not determine a child’s dose from age alone. The prescriber should calculate the dose according to body weight, infection, kidney function, and local prescribing guidance.

7. Reconstitution & Storage

• Add the required amount of clean water according to the manufacturer’s instructions to make the final volume of 60 mL.
• Shake well after adding water.
• Shake well before each dose.
• Use the supplied measuring device for accurate dosing.
• Follow the product leaflet for the exact storage period after reconstitution, as this can vary by formulation/manufacturer.

8. Packing Size

60 mL when reconstituted — 100 mg/5 mL oral suspension.