VONOPIN 20.MG TABLETS 14’s

VONOPIN 20 mg Tablets

Generic: Vonoprazan fumarate
Strength: 20 mg
Pack shown: 14 tablets
Drug class: Potassium-competitive acid blocker (P-CAB)

Vonoprazan is a potent gastric-acid suppressant used mainly for acid-related gastrointestinal disorders, including erosive esophagitis and, in combination with antibiotics, H. pylori infection.

1. Indications

VONOPIN 20 mg may be prescribed for:

• Erosive esophagitis — healing acid-related damage to the esophagus
• Relief of heartburn associated with erosive esophagitis
• H. pylori infection, when used together with appropriate antibiotics
• Other acid-related conditions according to the locally approved product information.

2. Benefits / Pharmacological Action

• Strongly suppresses gastric acid secretion
• Helps relieve heartburn and acid reflux symptoms
• Promotes healing of acid-damaged esophageal tissue
• Provides prolonged acid suppression
• Can be used as part of combination therapy for H. pylori eradication.

3. Usage / Dosage

For healing erosive esophagitis:
20 mg once daily for 8 weeks is the recommended adult dose in the current U.S. labeling.

For H. pylori infection: vonoprazan 20 mg is used with antibiotics. Regimens include:

• Vonoprazan 20 mg + amoxicillin 1,000 mg + clarithromycin 500 mg, twice daily for 14 days, or
• Vonoprazan 20 mg twice daily + amoxicillin 1,000 mg three times daily for 14 days.

Important: The H. pylori regimen should be prescribed by a doctor; do not use vonoprazan alone to treat H. pylori.

4. Contraindications

Do not use vonoprazan in patients with:

• Known hypersensitivity/allergy to vonoprazan
• Previous serious allergic reaction to the medicine
• Concomitant use of rilpivirine-containing products.

5. Side Effects

Possible adverse effects include:

• Diarrhea
• Abdominal pain/discomfort
• Nausea
• Abdominal bloating
• Constipation
• Headache
• Gastritis
• Changes in liver enzymes

Rare but serious reactions can include severe allergic reactions, kidney inflammation, severe skin reactions, and C. difficile-associated diarrhea.

6. Warnings & Precautions

Use with medical supervision in patients with:

• Liver disease
• Kidney impairment
• Low magnesium or other electrolyte abnormalities
• Long-term acid-suppression requirements

Persistent symptoms despite treatment should be evaluated because improvement with acid suppression does not completely exclude gastric malignancy.

Long-term acid suppression can also be associated with problems such as vitamin B12 deficiency, low magnesium and gastric fundic-gland polyps.

7. How to Take

• Take orally as prescribed.
• It can generally be taken with or without food.
• Take at approximately the same time each day.
• Swallow the tablet as directed; do not alter/crush it unless the product’s specific instructions permit this.

8. Packing Size

VONOPIN 20 mg — 14 tablets per box, according to the supplied image.